GnRH Analogues in the Prevention of Ovarian Hyperstimulation Syndrome
نویسندگان
چکیده
The GnRH analogue (agonist and antagonist GnRH) changed ovarian stimulation. On the one hand, it improved chances of pregnancy to obtain more oocytes and better embryos. This leads to an ovarian hyper-response, which can be complicated by the ovarian hyperstimulation syndrome (OHSS). On the other hand, the GnRH analogue can prevent the incidence of OHSS: GnRH antagonist protocols, GnRH agonist for triggering final oocyte maturation, either together or separately, coasting, and the GnRH analogue may prove useful for avoiding OHSS in high-risk patients. We review these topics in this article.
منابع مشابه
Comparison of Cabergoline with Quinagolide in Prevention of Severe Ovarian Hyperstimulation Syndrome among Patients Undergoing Intracytoplasmic Sperm Injection:A randomized trial
a:4:{s:9:"Objective";s:192:"The aim of the present study was to compare Quinagolide with Cabergoline in prevention of ovarian hyper stimulation syndrome among high risk women undergoing intra cytoplasmic sperm injection.";s:19:"MaterialsAndMethods";s:948:"Material and Methods: This Randomized clinical trial study was performed from March 2015 to February 2017. One hundred and twenty six women u...
متن کاملThe Role of GnRH-Analogues used in Elderly (>38 yrs) Patients Undergoing Controlled Ovarian Hyperstimulation for IVF
Studies comparing GnRH agonist long protocols with GnRH antagonist protocols have yielded conflicting results for pregnancy rate, and have related the lower pregnancy rate observed during GnRH antagonist cycles, to their use in cycles with an unfavorable prognosis a priori, i.e., repeated failures and elderly low responders [2-3]. Moreover, an increasing number of publications have appeared in ...
متن کاملCabergoline versus Coasting in the Prevention of Ovarian Hyperstimulation Syndrome and Assisted Reproductive Technologies Outcome in High Risk Patients
Background Coasting is the most common method used in the prevention of ovarian hyperstimulation syndrome (OHSS) acting through vascular endothelial growth factor (VEGF) reduction. However, the pregnancy rate is reported to fall with coasting when it takes more than three days. Recently lowdose cabergoline, a selective D2 dopamine receptor agonist has been proven to selectively reduce vascular ...
متن کاملOutcomes of GnRH agonist triggering in assisted reproductive technology: a systematic review
Objective: To make a review of studies that assessed the outcomes of GnRH agonist oocyte triggering in comparison with hCG in prevention of ovarian hyperstimulation syndrome and
متن کاملCurrent Medical Strategies in the Prevention of Ovarian Hyperstimulation Syndrome
The purpose of this review is to analyze current medical strategies in the prevention of ovarian hyperstimulation syndrome (OHSS) during ovarian stimulation for in vitro fertilization. Owing to contemporary preventive measures of OHSS, the incidence of moderate and severe forms of the syndrome varies between 0.18% and 1.40%. Although none of medical strategies is completely effective, there is ...
متن کامل